Host: Tata Institute For Research Centre for Applied Mathematics
Daniel Howard, a 2015 S.N. Bose scholar, spent his summer in Bengaluru, India at the Tata Institute of Fundamental Research, Centre for Applicable Mathematics (TIFR-CAM) with Prof. Praveen Chandrasekhar. Collaborating with Prof. Dinshaw Balsara from the University of Notre Dame, research work focused on computatonal fluid dynamics and discontinuous Galerkin methods. Daniel received his B.S. in Applied Mathematics, Engineering, and Physics (AMEP) from the University of Wisconsin-Madison in May 2015 and is now a Ph.D. graduate student at the University of Notre Dame in the Department of Applied & Computational Mathematics & Statistics (ACMS).
I'm a 4th year MD/PhD dual degree student, currently working towards my PhD in Epidemiology. My research interests are in the area of healthcare-associated infections, especially those related to antibiotic resistance and Clostridium difficile globally. Outside of work I enjoy cooking, photography, reading, and travel.
I went to India this past summer to complete my field work for my Masters in Public Health program. I did a qualitative research project on antibiotic resistance. I enjoyed learning more about public health along with learning about the Indian culture.
Host: Centre for Environmental Planning and Technology (CEPT) Univeristy
Jared Landsman is an MS student in the Building Science program at UC Berkeley. He received his BS in Civil Engineering from Cornell University in 2014. Through the Center for Building Energy Research and Development (CBERD), Jared is currently conducting research on occupant comfort and the performance of passive design strategies in buildings in both the United States and India. This past summer, Jared spent 6 weeks working with the Centre for Advanced Research in Building Science & Energy (CARBSE) at CEPT University in India.
"The Effect of Hepatits B Status on Drug Induced Hepatotoxicity from Anti-Tuberculosis Treatment" -- Treatment with antituberculosis medications often induces hepatotoxic effects, deemed drug induced hepatotoxicity. This can cause serious liver damage, increase likelihood of default, and complicate treatment. Chronic Hepatitis B co-infection is hypothesized to exacerbate this side effect. The Tibetan refugee population in India has both a high burden of Hepatitis B and Tuberculosis and thus provides a unique opportunity to study the interaction between these two diseases.
Jacob is studying multiple vulnerabilities among People Who Inject Drugs (PWIDs) - This research focuses on the scope for primary prevention among PWIDs in their injecting as well as sexual networks. This work also looks into scope for integrating sexual reproductive health services with maternal and child health services. He finds this topic very interesting looking at India’s HIV control programme (which looks at prevention programmes aimed at high risk groups for HIV) at one hand,and the existing social cultural structure with patriarchy and status of women and how these affect access to health on the other to understand various dimension of vulnerabilities for transmission in the population.
Pallav is studying Invariant Theory of General Linear Groups over Finite Fields - They are trying to describe the generators of the invariant ring of general linear groups over finite fields due to their action on a quotient subring of the polynomial ring
Santhoshini is studying approximating MAXDICUT in a streaming setting - They are working on finding a good approximation algorithm for finding Max DICUT of a directed graph with its edges coming in a streaming setting and they are working on lower bounds for the same
Vivek's lab is called "The Effect on the size distribution of the Nano-particles by the application of DC as well as AC Electric field to the Flame System with different geometry". Along with this they will also focus on doing charge fraction, size distribution measurement, and SEM TEM imaging of Nano-particles.
Poovizhi Rengasamy is studying the simulation and implementation of voltage quadrupler. For the purpose of electrofishing 240V AC generated in the boat is converted to 1200 V DC using power electronic switches.The simulation is done using PLECS software and has to be implemented in PCB board.Earlier the conversion from AC is done using manual switches and huge capacitors. After using power electronic circuit we are able to achieve the conversion with less capacitance values and also control can be done in the final output voltage which is also cheaper.
Sibendu is studying the ffective SINR measurement for wifi OFDM PHY layer abstraction. Actually present PHY layer abstraction has a default AWGN channel so we have a constant frequency independent SINR but to avoid interference and multi path fading we go for OFDM where a number of subcarrier frequency bands used to send parallel bit stream. So here SINR will be different in each frequency band so we get a SINR vector that we are trying to map in a single SINR by EESM and MIESM algorithm. The entire implementation will be done in NS3 where the SISO (Single Input Single Output) model exist so from the SINR vector got from MIMO model we will have a single SINR so that it can be equivalently fitted in that SISO.model
Kanika is studying the production of biofuels using Zymomomas using MEP pathway which is used to make isoprenoid. They are trying to clone 5 enzymes of this pathway and incorporate this plasmid into zymomonas for bioduels biofuels production
Murlidhar is fabricating scaffolds from blend of natural cell-interacting chitosan and lactide-polyethylene gylcol hydrogel followed by characterization of hydrogels which can further used for encapsulation of MSCs.
Richa's research is "NON UREMIC CALCIPHYLAXIS" highly fatal and extremely rare disease of “ Non Uremic Calciphylaxis ”, which has a reported mortality rate of 81% within 6 months of diagnosis , which is much more than many of the stage IV malignancies. It is an ischaemic vasculopathy characterized by the deposition of calcium within the media of small and intermediate dermal vasculature which can lead to epidermal ischaemia , ulceration and necrosis. It is usually seen in end stage kidney disease patients but i am working on that disease that develops in non kidney disease patients.
Sai Sinhu is working on Biosensors for small molecules based on Transcription Factors. They have transcription factor gene and a GFP transformed into a bacterial cell. So when the transcription factor goes and binds to promoter of GFP , the GFP is repressed. When the small molecule binds to transcription factor, it leaves the promoter making space for RNA polymerase to bind and GFP is expressed. So this GFP on Off helps us to sense how much small molecule is produced in the cell. I am checking which promoter for transcription factor will give us a good on-off signal. So they selected promoters which have diverse distributed protein production units and planning to transform them into bacterial cells and see how the GFP on off works.
Sridevi is studying homeostatic plasticity in cultured visual cortical neurons: The aim of the project will be to transfect cultured visual cortical neurons with a lentiviral construct expressing a mutant form of GRIP, a post synaptic protein and study the effect on homeostatic plasticity.
Host: Indian Institute of Technology (IIT) Kharagpur
2016 Khorana Scholar
Suriya is studying MR reconstruction using deep learning. Use of compressed sensing techniques allows MRI reconstruction from undersampled sparse K space data.To explore the use of specialised convolutional neural networks and autoencoders to learn optimal regulizers in reducing the motion artifacts and also reducing the computational time in compressed sensing based CEST(chemical energy saturation transfer) MRI reconstruction.
Ananth is studying polymer conformations in ionic liquids. The aim of the project is to find the dependence of polymer size on the molecular weight, when the polymer is dissolved in an ionic liquid. The polymers studied are PEO and NIPAM. The studies will be conducted using rheology and light scattering techniques.
Vishal is researching the detection of morphological differences in tissues in the context of osteoarthritis. His project is based on the registration of two images to analyse effect of bone development in osteoarthritis.
Richa is researching the synthesis and characterization of 2D materials. She will be using high temperature vacuum furnaces to grow GaSe thin film. And, then she will characterize the grown materials using Atomic force microscopy, Raman Spectroscopy and Photoluminescence spectroscopy she will characterize these materials and their opto-electronic properties.
Yashovardhan's proj is called et name is "Dynamic Searchable Encryption via Blind Storage”. He will be working on implementing and improving a solution developed by his professor to the problem of "Symmetric Searchable Encryption. He will be considering various security, efficiency and usability aspects of this construction.
Soundarya's project area is the Process Engineering and Energy. Brief description: It deals with supply chain management and finding the most optimized way for producing biofuel using regioanl depots and GAMs software.
Anuja's project is studying a norovirus is the most common cause of gastroenteritis in the world. The ORF1 of this virus encodes a polypeptide which is cleaved by a protease to form non structural proteins. The project is to study the effect of various protease inhibitors on the Houston variety of this virus (HOV) and find the most potent inhibitor of HOV protease.
The topic that Rhaul is studying is Rhodopsin Biosynthesis and Disc Formation in Rod Photoreceptor cell Description: Photoreceptor cells are a specialized type of neuron found in the retina that absorb and convert photons into electrical signals. They are essential for initiating the phototransduction cascade, which ultimately leads to visual perception. There are two types of photoreceptors: rods and cones. Rods are located in the outer regions of the retina and allow us to see in dim light as well as dark conditions. Rhodopsin is the light sensitive visual pigment in rods that allows humans to see in these low light conditions. Cones, on the other hand, reside mostly in the central portion of the retina and allow us to perceive fine visual detail and color. Both rods and cones are comprised of an outer segment full of discrete membranous discs, an inner segment, a nuclear layer, and a synaptic terminal. My project focuses on understanding rhodopsin biosynthesis and disc formation patterns in rod outer segments (ROS). It is widely accepted that disc formation in mammalian rods follows a 10-day cycle and light exposure increases disc phagocytosis at the apical end and increases lipid production at the basal end. Phagocytosis and degradation of ROS ensures functional integrity of the photoreceptor cells and other retinal cells. There are several factors, such as genetic or environmental factors, that can cause photoreceptor degeneration and eventual vision loss. Currently I am exploring how varying light conditions impact ROS renewal and rhodopsin incorporation into discs. Using a transgenic mouse that has a fluorescent marker attached to rhodopsin, I aim to understand the pattern of disc formation, rhodopsin biosynthesis in ROS, and the degenerative effect of light. This project can provide insight on how light exposure affects photoreceptors structure and function, which plays a key role in the visual process.
Agnimitra is working at the Transportation and Applied Econometrics Lab at Penn State. His work is to analyse multidimensional databases and statistical pattern specific to traffic safety. He is studying the accident severity based on sophisticated statistical models to investigate correlation with environmental factors, geometric design parameters of highways and Econometrics by using data analysis softwares like Excel, Limdep, Nlogit, R and STATA.
Aishwarya is working on the Columbia FlexICoN project,which is the " Full-duplex wireless from Integrated Circuits to Networks" project. She will be programming the interface to the self-interference cancellation circuit. Also, she would be implementing a OFDM PHY layer and other such schemes using a software defined radio platform with a programmable FPGA module in it. The group aims to make the full duplex communication more efficient and fast.
Akshaya is currently working in a cancer research laboratory. She mainly deals with ovarian cancer cell lines characterizing their protein expression by silencing several genes, and finding their proliferation, migration, invasion and colonisation capacity.
Alok is working at the Materials Research Institute at Penn State. He is studying the properties of 2D materials and learning the various methods to characterize them. He is using high-temperature vacuum furnaces to grow InSe, GaSe thin layers on Epitaxial Graphene. To study their properties he is using Scanning Electron Microscopy, Atomic Force Microscopy, Raman Spectroscopy etc.
Arnab is working on turbulence modeling using Partially Average Navier-Stokes (PANS) method with Prof. Girimaji at Texas A&M University. He will implement this technique on OpenFOAM, an open source efficient software package and he will capture the results of this numerical experiment by using ParaView software which is very efficient flow visualization software. However, the ultimate expectation of the work is to predict the behavior of complex turbulent flow in presence of any rigid structure which is very significant fluid-structure interaction (FSI) problem for growing Mechanical, Energy, Ocean and Aerospace Engineering field.
Avishek is using GPS and NASA satellite data to study the correlation of environmental parameters such as water vapor, pressure, rainfall with the occurrence of Hurricanes on both the east and west coast of USA. He will also study the long term characteristics of water vapor over USA. Later, if time permits, he may work on feature extraction from Landsat imagery data.
Baishali is working in membrane biophysics. Currently she is working on ER (Endoplasmic Reticulum) lipid Membrane remodeling in presence of viral (Poliovirus) peptides by Clearance Assay, CD Spectroscopy and Electron Microscopy.
Hrishikesh is working in the non destructive evaluation laboratory of Michigan State University under the guidance of Prof Lalita Udpa. He is involved in a project of design of simulation model for eddy current steam generator inspection. His work is to develop a noise simulator which is to be integrated to the model. It is done by injection of random and systematic noise into the signals and observing the corresponding changes in the output using signal processing techniques.
Jyostna is interning at Tulane University, in the department of Tropical medicine. My work is on the malarial vaccines. In this project she is studying the cross reactivity of two malarial antigens respectively from P.vivax and P. falciparum.The sequence similarity found via bioinformatics tools, was the foundation of this research. Now via western blotting, Immunofluorescence assay, ELISA and mammalian transfection techniques we are trying to see their epitope cross reactivity. Also, she is planning to study some epigenetic techniques.
Maharrish is working on tumor microenvironment. Immune cells, Endothelial cells, Stromal cells and Extra cellular matrix constitutes microenvironment which are all vital drivers for metastasis. He is working on CCR2 (molecule expressed by myeloid and tumor cells which is important for metastasis) Knock out mice and characterizing the efficacy of adopted CD8+ T cell transfer. He is also characterizing the antigens released by irradiated tumor cells that can activate Dendritic cells for active presentation and ultimately these antigens can be used in tumor therapeutic next generation vaccine.
Mahima is working on plasmonic photocatalysis, wherein visible light excitation of metal, especially gold and silver nanoparticles, is used to induce chemical reactions like carbon dioxide reduction and ethylene oxidation.It involves synthesis of the catalyst followed by monitoring the efficiency of the photocatalysis reaction. The methods of study used are gas chromatography, UV-Vis spectroscopy, and mass spectroscopy. The broad area of work is solar energy harvesting.
Mayuri research focuses on the synthesis and characterization of Cross-linked Polymerized Ionic Liquids. She will characterize them for their potential use as actuators, piezoelectric materials as well as in electro-adhesion with the help of AC-Impedance Spectroscopy. Other characterization techniques that she will use for analyzing the Polymer Ionic Liquid gel are Differential Scanning Calorimetry, Fourier Transform Infrared Spectroscopy, Nuclear Magnetic Resonance and Dynamic Mechanical Analysis.
Meghomita is working on understanding the deformation mechanism that characterized the Alleghanian plateau by looking at Microstructures taken from samples along the Towanda fault in Towanda, Pennsylvania.
Praneeth is exploring the frontiers of Internet of things by researching at the cross section of materials science, chemistry and engineering. He is working on developing innovative sensors for detecting toxic gases such as carbon monoxide. He is currently working on synthesizing magnetic gold nanoparticles that would be used to create 'smart polymer films' to produce a sensor that can change color on detecting traces of toxic gases and alert people of the impending danger well in advance.
Radha is creating an interface in Matlab to deal with loads of Epilepsy data from mices (which were on different diets-Fatty food reduces seizures-and then given seizures), to remove artifacts, select seizure onset and stop times and save relevant data for analysis in minimal time and automated manner. She'll be analyzing the same data later and derive relevant features and observations about seizures
Host: National Institute of Standards and Technology
Sandesh is working on applying Machine Learning to control quantum dot systems. He is developing an API for interfacing with current experimental setups, to enable a machine learning based approach for automated tuning of gates in a quantum dot architecture.
Satyaki is researching on a novel topology of DC-DC resonant converter. The proposed topology is supposed to act as a constant current source to the load in open loop operation, that is even if the load voltage changes the output current would remain constant. A typical application is automotive LED driver, where strings of LEDs may be connected to the load which require a constant current to turn them on, but the voltage varies as the number of LEDs change. My work is to analyse the topology analytically and verify the findings using simulation. I am also prototyping the converter in printed circuit board to carry out experiments using actual hardware. My work also involves finding out appropriate control strategies, to regulate the output current with variations in input voltage or output voltage and incorporate those to run the converter.
Siddhesh is working under Dr. Alvaro Pascual-Leone to evaluate neuroplasticity in patients with amnestic mild cognitive impairment (aMCI). He is using particular transcranial magnetic stimulation (TMS) protocols for this purpose. His project looks specifically at aMCI patients who do not have the significant (above prescribed threshold) Amyloid beta load in the brain regions associated with awareness about memory impairment and self-referential processing. He will also be doing related course work on TMS and tDCS offered here.
Soumi is researching on "Speech deterioration in Alzheimer's Disease". She will be collecting speeches and literary articles of politicians, author and other celebrities who had Alzheimer's. After which she will applying Machine Learning Algorithms to these texts to help the machine learn about the statistical trends in the speeches of these celebrities over the years of their life. The deterioration can be in the form of loss in memory resulting in stammering speeches. or increased used of fillers, or increased used of pronouns or some trend in the use of the various parts of speeches etc. All these factors will be taken into account to slowly answer our research questions.
Sriraksha is working under Prof. Paul Voyles at the Materials Science and Engineering department at UW-Madison. She will be synthesizing metallic glass thin films by sputtering. She will also be working on characterizing them by nano-indentation and X-ray photoelectron spectroscopy techniques.
Sudharsan is researching to understand the role of FMRP & FXR2P genes in the neurogenesis, a process affected in a number of neurological and neuropsychiatric disorders, including fragile X syndrome. His lab is attempting to figure out whether removing Fmrp in progenitor cells or immature neurons (DCX+ cells) harms their development in any way. He does genotyping and sectioning the brains using sliding microtome to mount the sections & trace neurons using Apotome microscope.
Sumanjit is at UChicago in Prof. Bryan Dickinson's lab, his project is primarily focused onto modifying the Split RNAP system by changing their binding partners with Ras and Raf proteins. Upregulation of these proteins have been shown to cause tumorigenesis and cancer, so they have become topics of intense research. Transfection of these protein chimeric constructs into mammalian cells and subsequent study of their biological properties would be helpful to understand the process better and help to develop inhibitors.
Sunil is studying circumgalactic medium (CGM) at low redshift. He is looking optical and IR spectroscopic data from the Lick and Keck telescopes and trying to characterise the medium around emission line galaxies (ELGs) or starforming galaxies through the spectral absorption features of background quasars.
Vrushali is assisting in a research project named-"Concrete Breakout Behaviour of Embed Plates with Welded Deformed Reinforcing Bars". She will be carrying out analysis using the software-ABAQUS by changing parameters in order to capture concrete breakout failure modes. The models will be calibrated with the data obtained from the experimental tests conducted previously. Meanwhile also gaining some lab floor experience by working with a team on-"Seismic Behaviour of Concrete Wall under Thermal effects ".
Asimanshu is working on the Ground Vibration test of the X-HALE a High Altitude Long endurance aircraft.The GVT data are used to validate analytical vibration and flight control models by measuring flight control transfer functions and structural frequency response functions. He is also validating it with standard FEM codes.This project is used to validate the non linear aeroelastic code UM -NAST developed by University of Michigan.
Shashank is researching on recent changes in glaciers with respect to mass budget and flow dynamics in Sikkim, India as a part of the 'NASA High Mountains of Asia Project'. He will be using medium to high resolution satellite images to derive DEMs and work on a time series using open source libraries. Additionally, he will assess the galcial lakes in the region and try to establish a link between glacier dynamics and lake growth pattern.
Mohit is currently working on Active Flow Control for drag reduction due to wall turbulence. He will be using blowing/suction actuation to suppress the turbulent coherent structures in the flow. The flow bed will have an array of sensors to detect the pressure fluctuations at the wall and blowing/suction will be performed accordingly. To design the experimental setup, simulations are performed using resolvent Spectral method.
Dhiman is working on computational analysis of nano-bio interface from molecular dynamics simulation. The charge of nanoparticles influence how they interact with biomolecules. He will use molecular simulation techniques with classical force fields to study the charge and mobility of nanoparticles in presence of external electric field and make predictions which can be compared with experiments.